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Metrics Contract Services Adds Bosch GKF-702 Encapsulator

Metrics Contract Services, a division of Mayne Pharma Group Limited, has added a Bosch GKF-702 capsule filling machine to its recently completed solid oral dose commercial manufacturing facility in Greenville, North Carolina, USA. The high precision machine is capable of manufacturing from 3,000 to 42,000 capsules per hour. It offers the flexibility of filling capsules and pellets.

“The new Bosch GKF-702 is a significant addition to our pharmaceutical development capability. It enables a versatile offering as it is designed for the encapsulation of micro tablets, powders, pellets, liquids and combination fillings. Its tamping pin design compliments Metrics’ IMA Zanazi dosator machine making Metrics Contract Services a future-proof developer of encapsulated products,” said Joe Cascone, Vice President of Metrics Contract Services.

“The improved performance and production upgrades in this model offer a high level of precision and efficiency that will enable us to keep up with the growing demands of our clients,” added Brad Gold, Vice President of Pharmaceutical Development for Metrics Contract Services. “The design improvements, such as the slide gate mechanism, mean easy maintenance, quicker change over, and higher yield due to less product loss.”

Based on the scope of projects and the demand of products progressing towards commercialization, the Bosch GKF-702 was the right choice for throughput and ease of transfer to commercial production. Metrics Contract Services works with numerous clients each year whose projects require encapsulation. The new Bosch is expected to work well in multiple clinical programs and with the company’s new HSM III high shear granulator.

The GKF 702 can produce small batches for R&D or clinical purposes. Its unique filling station, or “Mini-Bowl,” is designed for small product batches between 100 and 300 grams, which allows for higher powder yields which are economical for limited capsule volumes during the development phase.

About Metrics Contract Services

Metrics Contract Services is a full-service pharmaceutical development and manufacturing organization serving clients worldwide delivering proven scientific and operational excellence for oral dosage forms. Metrics’ areas of expertise include quality pharmaceutical formulation development; first-time-in-man formulations; Phase I-III clinical trial materials manufacturing; and analytical method development and validation services leading to commercial scale manufacturing. Technical capabilities include highly potent, cytotoxic and unstable compounds; Schedule II-V controlled substances; and products with poor bioequivalence, for which we offer an impressive proprietary portfolio of advanced delivery methods. Located in Greenville, N.C., Metrics is a proud member of Mayne Pharma. Learn more at

About Mayne Pharma

Mayne Pharma is a specialty pharmaceutical company listed on the Australian Securities Exchange (ASX: MYX) focused on the application of drug delivery expertise to commercialize branded and generic pharmaceuticals, providing patients with access to better and more affordable medicines. Mayne Pharma has a 30-year track record of innovation and success in developing new oral drug delivery systems, and these technologies have been successfully commercialized in numerous products that have been marketed around the world. Mayne Pharma has two drug development and manufacturing facilities based in Salisbury, Australia and Greenville, USA, with expertise in the formulation of complex oral and topical dose forms including potent compounds, modified-release products and inherently unstable compounds. For further information, visit